Epistemology is the study of how we know things. All of us cycle between two main ways of knowing in our modern culture: 1) the rational, reductionist way and 2) the holistic, relational, intuitive way. By far the most dominant way is the rational, reductionist way and our institutions, scientific, economic, financial and organizational are governed by this way of thinking.
For the reductionist thinker, everything in the universe is made up of parts. If we can understand the parts, we can understand the whole. Depending on the field, the physical world is nothing but atoms and molecules and the social world is nothing but self-maximizing, rational actors. The reductionist view is very powerful and filled with "nothing but" statements. It never occurs to the thoroughgoing reductionist that the idea of "parts" is merely a mental construct.
In our everyday relationships with friends and family, in our nonrational pursuits in music and the arts, in our religious lives, we tend toward the second way of thinking, holistic, relational and intuitive.